Vance: So, one, on the obsolescence point, I think the history of tech and innovation is that while it does cause job disruptions, it more often facilitates human productivity as opposed to replacing human workers. And the example I always give is the bank teller in the 1970s. There were very stark predictions of thousands, hundreds of thousands of bank tellers going out of a job. Poverty and commiseration.
reaching for Vertico, Consult, or Helm, I use icomplete-vertical-mode,,更多细节参见吃瓜
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全文总结本研究系统揭示了运动改善阿尔茨海默病认知障碍的肌 - 脑通讯机制:游泳运动诱导骨骼肌分泌富含 miR-378a-3p 的细胞外囊泡,该囊泡穿越血脑屏障后被小胶质细胞摄取,通过靶向 p110α 调控脂质代谢重编程,激活疾病相关小胶质细胞的淀粉样蛋白斑块清除功能,最终改善认知障碍。同时证实,过表达 miR-378a-3p 的肌管来源囊泡可模拟运动的治疗效果,为阿尔茨海默病提供了全新的运动模拟型靶向治疗策略,也为理解外周组织与中枢神经系统的通讯提供了新视角。
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